Pterocarpus marsupium Roxb and Alloxan-induced Diabetes Mellitus in Experimental Rabbits

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Antidiabetic, Antihyperlipidaemic and Antioxidant activity of Pterocarpus marsupium Roxb. in alloxan induced diabetic rats

Pterocarpus marsupium Roxb (Fabaceae) is a well known medicinal plant and is used in various human ailments. The ethanol extracts of Pterocarpus marsupium wood, bark and combined extract of wood and bark were investigated for its antidiabetic effect in Wistar albino rats. Diabetes was induced in Albino rats by administration of alloxan monohydrate (150mg/kg,i.p). The ethanol extracts of Pteroca...

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Memory enhancing activity of methanolic extract of Pterocarpus marsupium Roxb

The present study was undertaken to investigate the effects of methanolic extract of Pterocarpus marsupium Roxb. on learning and memory in albino mice. Two doses of methanolic extract of P. marsupium (25 and 50 mg/kg p.o.) were administered for neurotoxicity test. The mice administered with 25 mg/kg of the extract could significantly maintain the equilibrium on the rotating rod. Elevated plus-m...

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Therapy with methanolic extract of Pterocarpus marsupium Roxb and Ocimum sanctum Linn reverses dyslipidemia and oxidative stress in alloxan induced type I diabetic rat model.

Methanolic extracts of Pterocarpus marsupium Roxb (P. marsupium) and Ocimum sanctum Linn (O. sanctum) were prepared separately and then administered to both non-diabetic and alloxan induced diabetic adult female Wistar rats as a mixture of both at a dosage of 500mg/kg body weight, and its effect was checked on serum and tissue lipids together with corticosterone, estrogen and progesterone profi...

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Antidiabetic activity of heart wood of Pterocarpus marsupium Roxb. and analysis of phytoconstituents.

The crude powder, ethanolic extract and aqueous, chloroform, hexane and n-butanol soluble fractions of ethanolic extract of heart wood of P. marsupium showed marked improvement on oral glucose tolerance post sucrose load in normal rats. All these fractions except aqueous fraction showed improvement on oral glucose tolerance post sucrose load on streptozotocin (STZ)-induced diabetic rats. The cr...

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Evaluation of hepatoprotective activity of stem bark of Pterocarpus marsupium Roxb

Objective: To evaluate the hepatoprotective activity of Pterocarpus marsupium stem bark extracts against carbon tetrachloride (CCl 4 )-induced hepatotoxicity. Materials and methods: Hepatotoxicity was induced in male Wistar rats by intraperitoneal injection of CCl 4 (0.1 ml/kg/day for 10 days). Methanol and aqueous extracts of P. marsupium stem bark were administered to the experimental rats (2...

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ژورنال

عنوان ژورنال: Journal of Nepal Medical Association

سال: 2003

ISSN: 1815-672X,0028-2715

DOI: 10.31729/jnma.1829